Clinical Trials

FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06244004 Phase: PHASE2 Trial Summary: This phase II trial compares the effect of FDG-positron emission tomography (PET)-guided metastasis directed radiation therapy (MDRT) in combination with standard treatments to standard treatments alo – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): Northwestern University Acronym:

Internet-Based Lifestyle Intervention (iLIVE) to Eradicate Obese Frailty in Prostate Cancer Survivors

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06011499 Phase: Trial Summary: This clinical trial tests the effectiveness of an online weight loss plus resistance training intervention (iLIVE) to decrease obesity and improve frailty in men with prostate cancer who received andr – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): OHSU Knight Cancer Institute Acronym: iLIVE

A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06257758 Phase: PHASE1|PHASE2 Trial Summary: The goal of this phase 1/2 clinical trial is to investigate the safety of an investigational drug called VIO-01 when taken by people who have different types of solid tumor cancers. There are two part – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): Valerio Therapeutics Acronym:

Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06014255 Phase: PHASE2 Trial Summary: This study evaluates the efficacy, anti-tumor effect, and immunogenicity of neoadjuvant enoblituzumab given before radical prostatectomy. Patients will be randomized to enoblituzumab for a total of 12 – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Acronym: HEAT

Study of AZD0754 in Participants With Metastatic Prostate Cancer

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06267729 Phase: PHASE1|PHASE2 Trial Summary: The purpose of this study is to evaluate the safety, tolerability, and antitumour activity of AZD0754 CAR T-cell therapy in participants with metastatic prostate cancer. – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): AstraZeneca Acronym: APOLLO

Bortezomib in Patients With Metastatic Castration-Resistant Prostate Cancer With PTEN Deletion

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06029998 Phase: PHASE2 Trial Summary: The goal of this clinical trial is to test the anti-tumor activity of bortezomib in participants with Metastatic Castration Resistant Prostate Cancer (mCRPC) with PTEN Deletion. The main question[s – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): University of Utah Acronym: BORXPTEN

Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06296147 Phase: NA Trial Summary: The purpose of this study is to evaluate if a VR headset and/or aromatherapy can be used to reduce patient pain, anxiety, and embarrassment during a transperineal biopsy (TPBx) compared to standard of – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): University of Pittsburgh Acronym:

Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06040125 Phase: NA Trial Summary: The purpose of this study is to determine whether a 16-week supervised, clinic-based circuit training intervention utilizing resistance and functional exercises and self-directed aerobic exercise will – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): Dana-Farber Cancer Institute Acronym:

PSMA PET Response Guided SabR in High Risk Pca

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06044857 Phase: PHASE1 Trial Summary: Sequential cohort evaluation of ideal timing of imaging and treatment spacing to discern maximal PSMA (Prostate specific membrane antigen) PET (Positron Emission Tomography) response (PSMA-11 68Ga, Il – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): University of Texas Southwestern Medical Center Acronym:

PRCT001 Aquablation theraPy Outcomes in pRostate Cancer patienTs

April 3rd, 2024 | Clinical Trials

NCT Number: NCT06051942 Phase: NA Trial Summary: The goal of this clinical trial is to assess the performance and safety of the AQUABEAM Robotic System for the resection and removal of prostate tissue in patients experiencing lower urinary tract sym – see clinicaltrials.gov for information and location Clinicaltrials.gov Trial Sponsor(s): PROCEPT BioRobotics Acronym:

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