Clinical Trials Learning Sessions
PHEN provides Clinical Trial Learning Sessions in conjunction with cancer centers to bring Black patients and clinical trial doctors together to learn about clinical trials, and to build trust around clinical trial participation.
The phase 2 LEGION‑100 study is evaluating an investigational treatment called SYNC‑T Therapy SV‑102 for men with mCRPC. SYNC‑T SV-102 therapy is an outpatient procedure that involves placing a needle-like device into the tumor using image guidance (CT or ultrasound), followed by infusion directly into the tumor of the study drug (SV-102) to help the immune system fight cancer throughout the body and at the treated tumor site.
Together, the combination of breaking open tumor cells and then infusing SV-102, is designed to activate your immune system and educate it to recognize and attack cancer throughout your entire body.
Join Dr. Gerald L. Andriole, Jr., who is the Chief Medical Officer of Urology at Syncromune, as he explains:
- LEGION-100 SYNC-T Therapy
- Two treatment procedure steps
- Early findings and safety
Understanding the EvoPAR-Prostate02 Clinical Trial
This session focused on men with high-risk prostate cancer and a clinical trial called EvoPAR-Prostate02. The discussion was led by Dr. Keith Crawford with guest expert Dr. McKay, a genitourinary medical oncologist who treats prostate, kidney, bladder, and testicular cancers.
The goal was to help patients understand four main points:
- What high-risk prostate cancer means
- Why BRCA1 and BRCA2 testing may matter
- How PARP inhibitors may work
- What to ask before joining the EvoPAR-Prostate02 clinical trial
Understanding Omaha-003 and Omaha-004 Clinical Trials
This discussion explores the Omaha-003 and Omaha-004 clinical trials, including how these investigational treatments work to block hormones that help prostate cancer grow, the differences between the studies, and who may qualify to participate.
Topics Covered:
• Overview of metastatic castration-resistant prostate cancer (mCRPC)
• How investigational hormone-blocking therapies work
• Key differences between the Omaha-003 and Omaha-004 clinical trials
• Eligibility criteria and what participation may involve
• The role of clinical trials in advanced prostate cancer treatment
Understanding XALute Clinical Trial
The XALUTE clinical trial, sponsored by Amgen, is a research study evaluating an investigational treatment approach for prostate cancer, designed to assess safety and effectiveness while providing eligible patients access to innovative therapy options under closely monitored clinical care.
Understanding ARASTEP Clinical Trial
The ARASTEP clinical trial, sponsored by Bayer in collaboration with PHEN, is a prostate cancer research study evaluating whether the combination of darolutamide and androgen deprivation therapy (ADT) can delay disease progression in patients experiencing biochemical recurrence, with expert insights from Dr. Keith Crawford and Dr. Emmanuel S. Antonarakis to help patients with rising PSA levels understand eligibility, benefits, and participation in this important clinical trial.
Understanding EZH2 Clinical Trial
In collaboration with Pfizer, PHEN hosted a clinical trial learning session highlighting three coordinated Phase 3 studies evaluating a twice-daily oral EZH2 inhibitor added to standard-of-care treatment for men with metastatic castration-resistant prostate cancer (mCRPC), exploring whether combining the investigational therapy with agents such as enzalutamide can delay treatment resistance and slow disease progression, with expert insights from Dr. Keith Crawford and Dr. Neal Shore on eligibility, study design, side effects, and the importance of diverse participation.
Duke Cancer Institute
Clinical Trials Learning Session
Duke Cancer Institute physicians and the Prostate Health Education Network (PHEN) present a virtual session to learn about clinical trial opportunities available at Duke.
Johns Hopkins University
Clinical Trials Learning Session
Physicians from the Johns Hopkins University School of Medicine partner with PHEN to hold a virtual webinar and discuss clinical trial opportunities found at Johns Hopkins.
MSKCC
Clinical Trials Learning Session
Memorial Sloan Kettering Cancer Center’s physicians partnered with PHEN to present a virtual learning session about clinical trial opportunities available at MSKCC.
This information is for educational purposes only and not intended as medical advice.
Patients should consult their medical doctor for advice and recommendations about specific clinical trials.