Clinical Trials

Mevrometostat Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

July 30th, 2024 | Clinical Trials

NCT Number: NCT03460977 Phase: Phase 1 Trial Summary: A Phase 1 Dose Escalation and Expanded Cohort Study Of PF-06821497 In The Treatment Of Adult Patients With Relapsed/Refractory Small Cell Lung Cancer (SCLC), Castration Resistant P – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Pfizer Acronym: PF-06821497

A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

July 30th, 2024 | Clinical Trials

NCT Number: NCT05593497 Phase: PHASE2 Trial Summary: The purpose of this study is to learn about how an investigational drug intervention completed before doing prostate surgery (specifically, radical prostatectomy with lymph node dissection) may help i – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): VA Office of Research and Development Acronym: SNARE

CV CARE: CardioVascular Care in PC Patients

July 30th, 2024 | Clinical Trials

NCT Number: NCT06202820 Phase: NA Trial Summary: This research is being done to test a program to assess and manage reversible cardiovascular (CV) risk factors in participants with prostate cancer starting androgen deprivation therapy (ADT), with th – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Dana-Farber Cancer Institute Acronym:

A Trial for a Preliminary Estimate of the Effectiveness of a Novel Theoretical Framework

July 30th, 2024 | Clinical Trials

NCT Number: NCT06461416 Phase: NA Trial Summary: Aim 1: To determine the preliminary effect sizes of al ActiveHeal EST (Engage-Sustain-Triumph) Program on occupational resilience. – clinicaltrials.gov for more information and locations * Aim 2: To determine the preliminary effect sizes of ActiveHeal ES – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of […]

PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer

July 30th, 2024 | Clinical Trials

NCT Number: NCT06369246 Phase: PHASE2 Trial Summary: To look at the safety and effectiveness of stereotactic body radiation therapy (SBRT) in treating advanced or high-risk prostate cancer. – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): M.D. Anderson Cancer Center Acronym:

Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT

July 30th, 2024 | Clinical Trials

NCT Number: NCT06062745 Phase: PHASE1 Trial Summary: This research study is studying a positron emission tomography (PET) agent called 18F-fluciclovine to evaluate how well 18F-fluciclovine-PET scans determine the extent of advanced prostate cancer that – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Brigham and Women’s Hospital Acronym:

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

July 30th, 2024 | Clinical Trials

NCT Number: NCT06239194 Phase: PHASE1|PHASE2 Trial Summary: This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors. – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): ModeX Therapeutics, An OPKO Health Company Acronym:

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

July 30th, 2024 | Clinical Trials

NCT Number: NCT05919329 Phase: PHASE4 Trial Summary: This clinical trial investigates the change in prostate-specific membrane antigen (PSMA) expression in response to hormonal therapy in both, Castration Sensitive Prostate Cancer (CSPC) and Castration – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): OHSU Knight Cancer Institute Acronym:

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

July 30th, 2024 | Clinical Trials

NCT Number: NCT05113537 Phase: PHASE1|PHASE2 Trial Summary: This phase I/II trial tests the safety, side effects, and best dose of abemaciclib and whether it works before 177Lu-PSMA-617 in treating patients with castration resistant prostate cancer that has sp – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Vadim S Koshkin Acronym: UPLIFT

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

July 30th, 2024 | Clinical Trials

NCT Number: NCT06099093 Phase: PHASE4 Trial Summary: The purpose of this research study is to see how well an imaging test, called 18FDCFPyL prostate specific membrane antigen (PSMA) positron emission tomography (PET), can show the extent of prostate ca – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Brigham and Women’s Hospital Acronym:

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