Clinical Trials

Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management

July 30th, 2024 | Clinical Trials

NCT Number: NCT05799248 Phase: PHASE3 Trial Summary: Study Title: Role of rhPSMA-7.3 PET/CT imaging in men with High-Risk prostate cancer following conventional imaging and associated changes in medical management Protocol number: BED-IIT-437 Phase: 3b – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): MidLantic Urology Acronym:

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

July 30th, 2024 | Clinical Trials

NCT Number: NCT05939414 Phase: PHASE3 Trial Summary: The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prostate cancer (OMPC) progressing after defini – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Novartis Pharmaceuticals Acronym: PSMA-DC

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer

July 30th, 2024 | Clinical Trials

NCT Number: NCT05125016 Phase: Phase 1|Phase 2 Trial Summary: To assess the safety, tolerability, and pharmacokinetics (PK) and to determine recommended phase 2 dosing regimen (RP2DR) of REGN4336 separately as monotherapy or in combination wi – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Regeneron Pharmaceuticals Acronym:

Open-label, Multicenter Study of Intramuscular PRL-02 Depot in Patients With Advanced Prostate Cancer

July 30th, 2024 | Clinical Trials

NCT Number: NCT04729114 Phase: Phase 1|Phase 2 Trial Summary: A Phase 1/2a, open-label, multicenter study of intramuscular (i.m.) PRL-02 depot in participants with advanced prostate cance – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Astellas Pharma Global Development, Inc. Acronym:

Study in Patients With Advanced Cancers Associated With Expression of DLL3

July 30th, 2024 | Clinical Trials

NCT Number: NCT04471727 Phase: Phase 1|Phase 2 Trial Summary: A Phase 1/2 Open-label, Multicenter, Dose Escalation and Dose Expansion Study of the Safety, Tolerability, and Pharmacokinetics of HPN328 Monotherapy and HPN328 With Atezolizumab i – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, […]

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors

July 30th, 2024 | Clinical Trials

NCT Number: NCT04557449 Phase: PHASE1|PHASE2 Trial Summary: This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 administered as a single – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Pfizer Acronym: CDK4i

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial

July 30th, 2024 | Clinical Trials

NCT Number: NCT06378866 Phase: PHASE2 Trial Summary: This phase II trial studies the effects of stereotactic body radiation therapy (SBRT) and the timing of treatment with androgen receptor pathway inhibitor (ARPI) plus androgen deprivation therapy (ADT – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Mayo Clinic Acronym: DIVINE

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

July 30th, 2024 | Clinical Trials

NCT Number: NCT06150417 Phase: PHASE2 Trial Summary: The purpose of this study is to find out if giving radiation therapy (RT) to areas of metastatic prostate cancer at the time a participant is diagnosed will help control disease better than the usual – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Case Comprehensive Cancer […]

Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer

July 30th, 2024 | Clinical Trials

NCT Number: NCT06312670 Phase: PHASE2 Trial Summary: The purpose of this study is to study the effects of EPI-7386 in combination with Enzalutamide on participants diagnosed with prostate cancer. The main goals of this study are to evaluate the antitumo – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Pedro Barata, MD, MSc Acronym:

A Dose Finding Study of Debio 4228 in Participants With Locally Advanced/Metastatic Prostate Cancer

July 30th, 2024 | Clinical Trials

NCT Number: NCT06395753 Phase: PHASE2 Trial Summary: The primary purpose of this study is to determine the pharmacokinetics (PK) and pharmacodynamics (PD) of Debio 4228. – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Debiopharm International SA Acronym:

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