Clinical Trials

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

December 11th, 2023 | Clinical Trials

NCT Number: NCT05415098 Phase: Phase 1 Trial Summary: This is a multicenter, open-label, Phase 1 study that will be conducted in two parts. Part 1 is the dose escalation of APG-5918. Part 2 is the dose expansion of APG- – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Ascentage Pharma Group Inc. Acronym:

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

December 11th, 2023 | Clinical Trials

NCT Number: NCT05417594 Phase: Phase 1|Phase 2 Trial Summary: This study will assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AZD9574 individually and in combination with anti-cancer – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): AstraZeneca Acronym: CERTIS1

Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort

December 11th, 2023 | Clinical Trials

NCT Number: NCT05384535 Phase: Not Applicable Trial Summary: To determine whether using bpMRI in subjects who are at high risk of developing prostate cancer in conjunction with PSA will improve prostate cancer screening protoc – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Northwell Health Acronym:

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

December 11th, 2023 | Clinical Trials

NCT Number: NCT05413421 Phase: Phase 1 Trial Summary: The purpose of this study is to establish recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD) and preliminary antitumor activity of ORIC-944 in patients with metast – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): ORIC Pharmaceuticals Acronym:

T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High- and Intermediate-Risk Prostate Cancer Treated With Androgen Deprivation Therapy

December 11th, 2023 | Clinical Trials

NCT Number: NCT05361798 Phase: Phase 2 Trial Summary: Prostate cancer is often treated with radiation and ADT (ADT is androgen deprivation therapy). Up to 30% of these cancers recur within 5 years of treatment. Researchers want to see – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): National Cancer Institute (NCI)|National Institutes of Health […]

Patient-Reported Erectile Recovery and Quality of Life Outcomes With Lyopreserved Placental Tissue Applied Directly Over Neurovascular Bundle During Nerve Sparing Radical Prostatectomy Versus Standard of Care

June 23rd, 2023 | Clinical Trials

NCT Number: NCT05366842 Phase: Phase 2 Trial Summary: Surgical implantation of Lyopreserved Placental Tissue (LPT) is FDA approved and has been used extensively in wound care. The use is expanding and more recently, LPT has been used – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Johns Hopkins University Acronym:

AGN-CognI.Q Acute Dose Safety and Pharmacokinetics Dose-Response in Prostate Cancer Patients

June 23rd, 2023 | Clinical Trials

NCT Number: NCT05375539 Phase: PHASE1 Trial Summary: This study is to obtain acute dose safety and pharmacokinetics/pharmacodynamics (PK/PD) data in a dose-response trial in prostate cancer patients. – see link above for more informa – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Milton S. Hershey Medical Center Acronym:

AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc

June 23rd, 2023 | Clinical Trials

NCT Number: NCT05351424 Phase: NA Trial Summary: The study aims to develop educational media interventions to prepare Latinx Spanish-speaking radiation oncology patients for a course of breast or prostate cancer radiation therapy – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Columbia University Acronym: ADELANTE

An Imaging Agent (Perflutren Lipid Microspheres) With Ultrasound for Imaging of Prostate Cancer

June 23rd, 2023 | Clinical Trials

NCT Number: NCT05336786 Phase: Phase 3 Trial Summary: This phase III trial investigates if perflutren lipid microspheres with ultrasound can be used to diagnose prostate cancer non-invasively. Definity (perflutren lipid microspheres) – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Thomas Jefferson University Acronym:

Radiation Therapy and IRreversible Electroporation for Intermediate Risk Prostate Cancer (RTIRE)

June 23rd, 2023 | Clinical Trials

NCT Number: NCT05345444 Phase: Not Applicable Trial Summary: This is a single-site trial for 42 subjects with intermediate risk prostate cancer who undergo Irreversible Electroporation (IRE) followed by Magnetic Resonance guided Radiotherapy – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Weill Medical College of Cornell University Acronym: RTIRE

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