Clinical Trials

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer

December 11th, 2023 | Clinical Trials

NCT Number: NCT03860272 Phase: Phase 1 Trial Summary: This study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) profiles of a novel fragment crystallizable (Fc)-engineere – clinicaltrials.gov for more information and locations and locations Clinicaltrials.gov Trial Sponsor(s): Agenus Inc. Acronym:

A Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patients

December 11th, 2023 | Clinical Trials

NCT Number: NCT05679388 Phase: Phase 1 Trial Summary: Researchers leading this study hope to learn about the safety of combining the study drug relugolix with another study drug called itraconazole or ritonavir in prostate cancer. Thi – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of Chicago Acronym:

Weight Loss Interventions to Reduce Cancer Progression in Prostate Cancer Patients Under Active Surveillance

December 11th, 2023 | Clinical Trials

NCT Number: NCT05764330 Phase: NA Trial Summary: This clinical trial examines weight loss interventions in reducing cancer progression in prostate cancer patients under active surveillance. Intensive lifestyle interventions that – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Roswell Park Cancer Institute Acronym:

A Study on the Effects of Exercise Therapy on Signs of Prostate Cancer

December 11th, 2023 | Clinical Trials

NCT Number: NCT05751434 Phase: Phase 2 Trial Summary: The purpose of this study is to find out the effects of exercise therapy on indicators of prostate cancer in people with low-risk prostate cancer who are on active surveillance. Th – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Memorial Sloan Kettering Cancer Center Acronym:

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

December 11th, 2023 | Clinical Trials

NCT Number: NCT05722288 Phase: PHASE2 Trial Summary: This phase II trial studies how well time-restricted eating works in reducing side effects of radiation or chemoradiation side effects when compared to nutritional counseling among – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): City of Hope Medical Center Acronym:

A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours

December 11th, 2023 | Clinical Trials

NCT Number: NCT05605522 Phase: Phase 1 Trial Summary: This is a first-in-human Phase 1 clinical trial designed to investigate the safety, tolerability, pharmacokinetics, and biodistribution of [225Ac]-FPI-2059 and [111In]-FPI-2058 – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Fusion Pharmaceuticals Inc. Acronym:

Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

December 11th, 2023 | Clinical Trials

NCT Number: NCT05629494 Phase: Phase 4 Trial Summary: Prostate cancer is the most frequently diagnosed cancer in men in the Unites States. Nearly 1 million prostate biopsy procedures are performed in the United States annually and ele – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Albany Medical College Acronym: ADAPT-PSA

MRI Screening in Men at High Risk of Developing Prostate Cancer

December 11th, 2023 | Clinical Trials

NCT Number: NCT05608694 Phase: Not Applicable Trial Summary: The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of develop – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of Chicago Acronym:

T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer

December 11th, 2023 | Clinical Trials

NCT Number: NCT05586360 Phase: Phase 2 Trial Summary: This study will evaluate whether simvastatin reduces intraprostatic immunosuppressive microenvironment through YAP-mediated T-reg dysfunction, and increases intraprostatic anti-tum – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Medical University of South Carolina Acronym:

A Study Called ARAMON to Learn to What Extent Does Study Treatment With Darolutamide Affects Testosterone Levels in Men With Prostate Cancer That Had Not Been Treated With Hormonal Therapy Compared to Treatment With Enzalutamide

December 11th, 2023 | Clinical Trials

NCT Number: NCT05526248 Phase: Phase 2 Trial Summary: Researchers are looking for a better way to treat men who have biochemically recurrent hormone-naive – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Bayer Acronym: ARAMON

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