Clinical Trials

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

February 27th, 2024 | Clinical Trials

NCT Number: NCT04423211 Phase: Phase 3 Trial Summary: This phase III trial compares the addition of apalutamide, with or without targeted radiation therapy, to standard of care treatment versus standard of care treatment alone in pati – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): ECOG-ACRIN Cancer Research Group|National Cancer Institute (NCI)|Eastern Cooperative Oncology […]

Study of ADXS-504 Immunotherapy for Recurrent Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT05077098 Phase: Phase 1 Trial Summary: To evaluate the safety and tolerability of ADXS-504 and to determine the MT – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Mark Stein Acronym:

Optimizing Timing of rhPSMA-7.3 (18F) for Assessing Site(s) of Recurrent Disease Following Radical Prostatectomy

February 27th, 2024 | Clinical Trials

NCT Number: NCT05678322 Phase: Phase 3 Trial Summary: All men following Radical Prostatectomy (RP) at NYU Langone Health undergo routine prostate specific antigen (PSA) testing in order to identify disease recurrence. By consensus, a – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): NYU Langone Health Acronym:

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04812366 Phase: Phase 2 Trial Summary: The objective of this study is to see if providing an appropriate therapy based on the genomic testing of prostate tumour tissue will result in an improved clinical response. Each participant will be – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of British Columbia […]

Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04989946 Phase: Phase 1|Phase 2 Trial Summary: The current protocol will examine the use of a plasmid DNA vaccine encoding AR, alone or with nivolumab, to induce and/or augment therapeutic T-cells following androgen deprivation – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of Wisconsin, Madison Acronym:

Focal US-guided Cryo-ablation Using DynaCAD / UroNAV Preplanning / Guidance of Intermediate Risk Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04656678 Phase: Not Applicable Trial Summary: The purpose of this research study is to determine the safety and feasibility of using the UroNav software and DynaCAD software for planning and treating prostate cancer as an add – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Northwell Health Acronym:

An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT05454488 Phase: Phase 2 Trial Summary: To learn if using cryotherapy to treat only the part of the prostate known to contain cancer is effective in controlling pros – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): M.D. Anderson Cancer Center Acronym:

Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04402151 Phase: Phase 2 Trial Summary: This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Weill Medical College of Cornell University Acronym: PSMA SBRT-SIB

RESIST-ADT (Androgen Deprivation Therapy)

February 27th, 2024 | Clinical Trials

NCT Number: NCT04485767 Phase: Not Applicable Trial Summary: The overall goal of this study is to determine if implementing structured exercises prevent decline in muscle mass, muscle strength and physical function in men with prostate cance – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Dana-Farber Cancer Institute Acronym:

Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

February 27th, 2024 | Clinical Trials

NCT Number: NCT05489211 Phase: Phase 2 Trial Summary: TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination with Anticancer Agents – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): AstraZeneca Acronym:

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