Clinical Trials

Diet and Physical Activity Intervention for the Prevention of ADT-Induced Metabolic Changes in Patients With Prostate Cancer, TRIPLE-A PILOT Study

February 27th, 2024 | Clinical Trials

NCT Number: NCT04870515 Phase: Not Applicable Trial Summary: This clinical trial studies the effects of a diet and physical activity intervention on blood measures of lipids and insulin resistance in patients with prostate cancer undergoing – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Fred Hutchinson Cancer Center Acronym:

TRANBERGA® Transperineal MR/US Fusion Laser–Induced Thermal Therapy for Men With Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT05698576 Phase: Not Applicable Trial Summary: This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia. It will assess the tolerance and s – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Urological Research Network, LLC Acronym: TPF-LITT

Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04943536 Phase: Phase 1 Trial Summary: This study will be undertaken to evaluate the feasibility of replacing systemic Androgen Deprivation Therapy (ADT) with targeted local delivery of an anti-androgen agent alone in p – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Alessa Therapeutics Inc. Acronym: BiolenRT

PSMA-PET to Guide Prostatectomy

February 27th, 2024 | Clinical Trials

NCT Number: NCT05381103 Phase: Phase 2|Phase 3 Trial Summary: In this study, 288 patients will be randomized 1:1 to either having only the standard of care MRI prior to surgery versus having the standard of care MRI and the PSMA PET scan. PET – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Five Eleven […]

Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With BRCA1/2 Gene Alterations

February 27th, 2024 | Clinical Trials

NCT Number: NCT05498272 Phase: Phase 2 Trial Summary: Phase 2 open-label, single-arm clinical trial evaluating the efficacy and safety of neoadjuvant olaparib + LHRH agonist administered for 6 months prior to radical prostatectomy (RP – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Rana McKay, MD Acronym: NePtune

Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT05628363 Phase: Not Applicable Trial Summary: This trial is a prospective clinical trial designed to demonstrate the safety and feasibility of whole-pelvis adaptive prostate stereotactic body radiation therapy (SBRT) with a tu – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Washington University School of Medicine Acronym:

Study of ADXS-504 Immunotherapy for Recurrent Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT05077098 Phase: Phase 1 Trial Summary: To evaluate the safety and tolerability of ADXS-504 and to determine the MT – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): Mark Stein Acronym:

Optimizing Timing of rhPSMA-7.3 (18F) for Assessing Site(s) of Recurrent Disease Following Radical Prostatectomy

February 27th, 2024 | Clinical Trials

NCT Number: NCT05678322 Phase: Phase 3 Trial Summary: All men following Radical Prostatectomy (RP) at NYU Langone Health undergo routine prostate specific antigen (PSA) testing in order to identify disease recurrence. By consensus, a – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): NYU Langone Health Acronym:

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04812366 Phase: Phase 2 Trial Summary: The objective of this study is to see if providing an appropriate therapy based on the genomic testing of prostate tumour tissue will result in an improved clinical response. Each participant will be – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of British Columbia […]

Androgen Deprivation, With or Without pTVG-AR, and With or Without T-Cell Checkpoint Blockade, in Patients With Newly Diagnosed, High-Risk Prostate Cancer

February 27th, 2024 | Clinical Trials

NCT Number: NCT04989946 Phase: Phase 1|Phase 2 Trial Summary: The current protocol will examine the use of a plasmid DNA vaccine encoding AR, alone or with nivolumab, to induce and/or augment therapeutic T-cells following androgen deprivation – clinicaltrials.gov for more information and locations Clinicaltrials.gov Trial Sponsor(s): University of Wisconsin, Madison Acronym:

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